[DC Chemicals] Uramustine

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[DC Chemicals] Uramustine

 

Field of application:

Uramustine (INN), also known as uracil mustard, is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil.

 

Chemicals Properties
Cas No.:	66-75-1
Chemical Name:	5-(Bis(2-chloroethyl)amino)pyrimidine-2,4(1H,3H)-dione
SMILES:	O=C1NC(C(N(CCCl)CCCl)=CN1)=O
Formula:	C8H11N3O2Cl2
M.Wt:	252.09784
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Synonyms:	5-(Bis(2-chloroethyl)amino)pyrimidine-2,4(1H,3H)-dione

 

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